difference between significance and meaningfulness

Would you rather have results that are reliable or valid? Explain why? Under what conditions one would be achieved without the other? Give examples to illustrate your points.
Assignment 5
What is the difference between significance and meaningfulness? Which one is more important to experimental results and why do you think so?
Assignment 6
What is the value of case study analysis? How do results from a case study analysis differ from results from traditional qualitative and quantitative research? Explain why?